The 617 million dollar question your parents want answered

What is the 617 million dollar question? The aged population is increasing faster than any other on earth and soon–if not already–there’ll be even more people aged 65+ than under the age of 5. The 617 million dollar question comes when everyone aged 65+ gives a dollar to answer ‘how can we age healthy?’

Yes, there are 617 million people aged 65+ on the planet, and that’s just current estimates. By 2050, it’s expected that this number will more than double, while the world population will go up by only about a third. Europe will have roughly a quarter of its population aged 65+. And while the top 4 ‘oldest countries’ now are Japan, Germany, Italy, and Greece, by 2050 it’ll be Japan, South Korea, Hong Kong, and Taiwan. We’re all getting older, fast, and if you keep reading the numbers in the report from the US Census Bureau, you’d give a dollar for healthy aging too, no matter your age. Continue reading

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Should I take metformin for aging?

The antidiabetic drug metformin has been gaining lots of attention. This fame is well deserved since it extends lifespan in worms, mice, and there’s a clinical trial going on for human aging1. If you feel you’re getting older you might ask yourself should I should take metformin too? There’s just one thing to consider. Continue reading

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Men die, women suffer

It is well known that men die earlier than women. The sad part is that women live longer than men, but in worse health1, a trend that exists across many different countries2. If we can understand why, we can do something about it. Can we get women to live with the health benefits of men, and men to live as long as women?

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Can 23andMe tell me how long I’ll live?

23andMe can tell you something about your ancestry and can scare the crap out of you from all the genetic disease risks you might have, but can it also say something about your longevity? Scientists have also looked at the same kind of data 23andMe generates about you, and happen to have found three very important places in your genome that might say something about how long you’ll live1.

These three places in your genome are in just two genes: the stress response related FOXO3 and the cholesterol related APOE. The genetic locations, called ‘single nucleotide polymorphisms,’ or ‘SNPs’ for short, were found to have certain nucleotides (which are Gs, Ts, As, or Cs, the famous genetic code) be more commonly present in people of advanced age throughout the world. That means they might help you reach that age if you have them too.

So what are they? Continue reading

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How a Snicker’s bar is healthy

Inside all of us, there is an enormous, passionate, slightly obese, Raccoon. Though quite sociable, Raccoon unfortunately has one main drive in life: Snicker’s bars. It is often going full-throttle on it. Obviously, the more Raccoon gets satisfied, the less you have of a healthy life expectancy. What you might not realize though, is that Raccoon’s passion is made up of only three things: proteins, fats, and carbohydrates. In fact, all your food is mainly made of these. Raccoon doesn’t care about those measly little micronutrients, the vitamins and minerals, and right now, nor should you. This is about the big stuff, the so-called macronutrients that have an enormous effect on your life.

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The what, why and how of aging

What is aging, why does it happen, and how? Good questions.

What is aging?

Here it’s pretty well accepted, aging makes you more likely to die, and you are going to die of a disease. That simple. (Assuming you are lucky enough to not die from an accident or the violence of this world). You might want to read more about the top causes of death and what we should do about it. The next question starts to get a bit trickier now:

Why does aging happen?

This is basically asking ‘why does aging even exist’?! Well, why should we not age? The answers to ‘why’ questions in biology usually root themselves in evolutionary theories. For example, why don’t penguins fly? Or Ostriches? This might be because something else was more important for evolution than to have them fly, such as swimming better or running faster. For aging, something like this might be the case too. Why do we not live forever? Presumably, something else has been more important. For this answer, you’ll want to read more about the evolution of lifespans and watch a video on the differences between lifespans in mammals. And for the question that might have got you to this page:

What causes aging?

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Your typical day on your way to 120

Good morning, Matt. Digital birds are chirping as a soft alarm-clock light fills the room. You are waking up to the start of a new day, on the lovely road of longevity.

07h00: Rise and shine!

You leap out of bed to greet the day. You love those birdies Matt, no one is pushing you but yourself out of bed this morning. You know that just having a sense of purpose and meaning in life is already good for your lifespan1.

07h30: Breakfast

You forget about the frosty puffed-corn-wheat flakes and instead you go for longevity food: Continue reading

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The (obvious) 6 questions for a longer life

Being obvious and impactful, it is important to not get these wrong in your life. Ask yourself these six questions. Continue reading

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The best questionnaires: know if you will live to see your grandkids or Elon Musk go to Mars

The death test, the real age, and a bunch of lifespan predictors later, and where do we get? You want to know if you’ll live to see your grandchildren, if you need to plan a retirement, or if you will ever get to see Elon Musk go to Mars. Hey, I like Mars too. So I’ve trialled some of the more popular question-to-lifespan predictors, which say they can estimate how long someone will live, in the hopes of getting answers. Here are the results for what age they think I’ll manage: Continue reading

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6 physical tests to see how well you’re aging

Sure, they sound like tests the police might give you to check if you’ve been drinking too much, but these are in fact real ways you can see how well you’re aging, right at home. Why do these correlate so well to survival during aging? Performing these tests requires the heart, lungs, circulatory system, nervous system, and skeletal muscles to work efficiently and together, and therefore reflects the general youthfulness of your body. No wonder one study even found that just knowing your gender, age, and the speed at which you walk, was as accurate at predicting survival as was knowing your gender, age, chronic conditions, smoking history, blood pressure, body mass index, and hospitalization histories1. That’s impressive. So here are the tests, give them a try:

Walking speed test

walking speed testThis one is a walk in the park. Walk in a strait line, with a known distance of somewhere between 4-10 meters. Time yourself. Determine your walking speed (divide your walking time by the distance walked). Rule of thumb: if your speed is above 1 meter per second (about 100 times faster than a garden snail), you are doing great1.

Blinded one leg balance test

blind balance testThis one sounds the most like an alcohol test. Close your eyes and bend your knee to lift one foot off the ground. How long can you balance? Rule of thumb: make it to 30 seconds and you are a top performer. You can go back into the pub you were just pulled out of, and/or go on living a long healthy life. Actually it’s no joke. One study found that scoring less than 20 seconds (with eyes open though) was associated to having ‘silent’ strokes (lacunar infarctions), something which often precedes actual strokes, and dementia2.

Hand grip strength test

hand grip strength testThis is the most well characterized estimate of how you’re physically aging, but it might in fact be the hardest to do at home. You need a hand grip strength tester. I don’t have one. If you have one, squeeze it. Hand grip strength steadily increases throughout youth, peaking somewhere between age 29-39 in men (with a median of 51kg worth of squeeze-power) and 26-42 in women (squeezing a median of 31kg worth). It undergoes a minimal decline thereafter, with a much more obvious decline starting around age 60. While the optimal-health values will be different at each age, let’s put it this way: at the age of 80, half of men squeeze less than 32kg worth, and half of women squeeze less than 19kg worth3.

Chair rise test

chair rise testLike all the tests here, there are a variety of ways to do this one too. One way is by sitting in a chair and counting how many times you can stand up (with locked knees) and sit back down, in 30 seconds. This is probably the easiest for you to do right now, since you are reading this and most likely seated. Try it, now. Unlike the hand grip strength test, this one is mainly informative at ages above 60. If you are younger than that though try it anyways and you should aim for getting at least 14 chair rises if you are a man, and 12 if you are a woman in those 30 seconds. Here is a breakdown of what that the Center for Disease Control in the US (CDC) recommends getting at each age group:

Chair rise test - check your age Continue reading

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